Rocket is seeking an individual who will work within the R&D team supporting nonclinical development. The ideal candidate will be responsible for independently planning and executing in vitro and in vivo nonclinical pharmacology, efficacy, and safety/toxicology studies, with a very strong background in Biological Sciences.
The Senior Scientist will be highly collaborative, and will adhere to established processes, policies, and quality systems for conducting experiments and reporting data from basic research studies, regulatory toxicology programs, and other activities in support of Rocket’s gene therapy pipeline.
This is an exciting opportunity to actively contribute to ongoing translational research efforts aimed at developing potential therapeutics for life-threatening diseases utilizing gene therapy.
- Independently plan and execute experiments for inclusion in regulatory submissions, including pharmacology and toxicology; select approach and methods to achieve project objectives both by reference to the general body of scientific knowledge and by application of sound experimental procedure
- Provide oversight and management of research conducted by CROs and other third parties
- Analyze and evaluate experimental data and summarize findings and relevance to both project and company objectives
- Develop and outline research objectives consistent with company priorities and resources
- Write and review nonclinical study reports and relevant sections of regulatory documents
- Work closely with cross functional team members to ensure all work is completed with high quality in a timely and scientifically rigorous manner
- MS or Ph.D. in Biological Sciences or related field
- 2+ years (Ph.D.) or 5+ years (MS) of nonclinical R&D experience in pharmaceutical or biotech setting
- Mastery of standard wet lab techniques and prior experience working with viral vectors (preferably AAV)
- Hands-on experience in molecular biology including, designing and executing studies employing DNA/RNA extractions, PCR, qPCR, ELISA, western blot, immunolabeling (IHC and/or ICC, IF) on fixed sections, histological techniques and microscopy
- Has depth of knowledge and hands-on tissue culture expertise, especially working with iPS cells
- Good understanding of US FDA and European nonclinical regulatory requirements with hands-on experience generating study reports and other regulatory documentation supporting submissions
- Ability to operate in a fast-paced, collaborative environment with a “can-do” attitude
- Demonstrate strong verbal, written, and interpersonal communications skills with the ability to explain complex concepts with clarity and simplicity
Interested in joining our team?
Contact us today!
Resumes with cover letters may be submitted to firstname.lastname@example.org